We are seeking an Associate Director or Director of Product Management to spearhead the strategy, development, and commercialization of our oncology diagnostic algorithms and data products. Powered by our proprietary cell-free DNA (cfDNA) platform and one of the world's largest longitudinal clinico-genomic datasets, this role translates complex machine learning outputs into validated standard-of-care tools for cancer detection and biopharma partnerships. Reporting directly to the Senior Director of Product Management - Oncology Innovations, this position operates with broad technical and commercial autonomy to bring algorithm-driven solutions from concept through analytical validation. This is an ownership role for a builder who wants to eliminate functional silos and use data to pressure-test product assumptions in a fast-paced, science-driven environment.
PRIMARY RESPONSIBILITIES:
Product Strategy and Roadmap Ownership
Own the multi-year product roadmap for AI-powered diagnostics, resolving complex data science and commercial priorities by grounding product milestones in clinical validation data
Isolate and pressure-test high-value innovation opportunities to build a differentiated pipeline of AI-enabled diagnostic algorithms and biopharma data products
Translate large, longitudinal genomic and real-world datasets into clinically meaningful, regulatory-ready algorithms that address unmet clinical needs
Establish clear, unvarnished product requirements and data validation metrics for prospective algorithm pipelines
Algorithm Development and Lifecycle Management
Lead cross-functional execution across the full lifecycle—from initial concept and analytical validation through health-authority navigation and commercial launch
Partner closely with Bioinformatics, AI Research, and Data Science teams to translate next-generation sequencing data into robust algorithms supporting molecular residual disease (MRD) monitoring and therapy response prediction
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Advance priority algorithm concepts through proof-of-concept testing and coordinate analytical validation strategies
Formulate and launch data product pilots with target biopharma and clinical trial partners to maximize data utility and commercial relevance
Cross-Functional Leadership and Stakeholder Alignment
Align matrixed scientific, clinical, regulatory, and commercial teams to keep complex, data-driven products moving forward past operational bottlenecks
Coordinate product execution loops with teams across Clinical Genomics Database (CGDB), AI Research, and Biopharma Business Development
Communicate with technical and scientific precision when engaging biopharma partners and academic key opinion leaders (KOLs)
Maintain a transparent, fast-iterating product methodology, utilizing data to guide decisions and ensuring algorithms are commercially viable and scalable
QUALIFICATIONS:
Advanced degree (PhD, MD, MS, or MBA preferred) paired with 8+ years of total experience within biotechnology, diagnostics, or pharma-facing data products.
5+ years of dedicated product management experience within molecular diagnostics, genomics, or life sciences data platforms
Documented track record of leading complex data or diagnostic products completely through the lifecycle from early concept to on-market commercialization
Direct experience partnering with bioinformatics, computational biology, or data science teams to develop or commercialize algorithm-driven software assets
Deep experience working with large-scale genomic datasets, multi-omic frameworks, or clinical real-world evidence (RWD)
KNOWLEDGE, SKILLS, AND ABILITIES:
Deep structural understanding of oncology diagnostics, biomarker validation workflows, clinical trial architectures, and emerging liquid biopsy technology
Technical data fluency with the capability to engage as a peer with artificial intelligence researchers and computational biologists
Ability to navigate evolving health-authority regulatory frameworks governing machine learning and AI-enabled diagnostics
Strong ownership mindset with a proven record of balancing multiple structural innovation opportunities under tight timelines
Precise written and verbal communication styles with a commitment to scientific rigor and data transparency
The pay range is listed and actual compensation packages are based on a wide array of factors unique to each candidate, including but not limited to skill set, years & depth of experience, certifications and specific office location. This may differ in other locations due to cost of labor considerations.
Remote USA
$174,700—$230,000 USD
OUR OPPORTUNITY
Natera™ is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives.
The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other. When you join Natera, you’ll work hard and grow quickly. Working alongside the elite of the industry, you’ll be stretched and challenged, and take pride in being part of a company that is changing the landscape of genetic disease management.
WHAT WE OFFER
Competitive Benefits - Employee benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents. Additionally, Natera employees and their immediate families receive free testing in addition to fertility care benefits. Other benefits include pregnancy and baby bonding leave, 401k benefits, commuter benefits and much more. We also offer a generous employee referral program!
For more information, visit www.natera.com.
Natera is proud to be an Equal Opportunity Employer. We are committed to ensuring a diverse and inclusive workplace environment, and welcome people of different backgrounds, experiences, abilities and perspectives. Inclusive collaboration benefits our employees, our community and our patients, and is critical to our mission of changing the management of disease worldwide.
All qualified applicants are encouraged to apply, and will be considered without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, age, veteran status, disability or any other legally protected status. We also consider qualified applicants regardless of criminal histories, consistent with applicable laws.
If you are based in California, we encourage you to read this important information for California residents.
Please be advised that Natera will reach out to candidates with a @natera.com email domain ONLY. Email communications from all other domain names are not from Natera or its employees and are fraudulent. Natera does not request interviews via text messages and does not ask for personal information until a candidate has engaged with the company and has spoken to a recruiter and the hiring team. Natera takes cyber crimes seriously, and will collaborate with law enforcement authorities to prosecute any related cyber crimes.
For more information:
BBB announcement on job scams
FBI Cyber Crime resource page
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