Senior Data Scientist

Career Category

Clinical

What you will do

Let's do this. Let's change the world. We are seeking a Senior Data Scientist with expertise in quantitative pharmacology, PBPK/PK/PD modeling, and translational simulation to support biologics discovery. In this vital role, you will develop and apply fit-for-purpose mechanistic modeling and simulation approaches that help discovery teams interpret complex biological and pharmacology information, generate testable hypotheses, and make data-driven decisions. You will work with appropriate scientific data in secure, governed environments while ensuring modeling assumptions, documentation, and outputs are reproducible and decision-ready.

The successful candidate will work in a collaborative, multidisciplinary environment, partnering with scientists, data scientists, translational modelers, pharmacology experts, and discovery teams to design modeling strategies, evaluate uncertainty, and translate quantitative insight into actionable recommendations.

Key Responsibilities

- Develop and apply PBPK, TMDD, PK/PD, exposure-response, and related quantitative models for biologics discovery and translational questions

- Translate complex scientific information into quantitative assumptions, scenarios, and simulations that support model-informed decision-making

- Build reproducible workflows for parameter estimation, model calibration, sensitivity and uncertainty analysis, documentation, and review

- Apply statistical, machine learning, or Bayesian methods where appropriate to support parameter inference, model updating, and scenario analysis

- Partner with experimental and translational teams to align modeling plans, interpret results, and identify fit-for-purpose data needs

- Communicate modeling assumptions, limitations, uncertainty, findings, and recommendations clearly through reports, visualizations, and presentations

- Contribute to scalable model-informed drug design practices and reusable modeling frameworks that can support biologics discovery programs

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The collaborative professional we seek is a Senior Data Scientist with these qualifications.